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On a 100-degree day, it can surpass 170 degrees

In the published Phase 1/2 data, the clinical signature is consistent with that pharmacology: strong appetite suppression (GLP-1R-mediated), preserved glycemic control and improved tolerability versus pure GLP-1 agonists at equivalent weight-loss doses (GIPR-mediated), and meaningful thermogenic/fat-oxidation contribution above and beyond dual GLP-1/GIP activity (GCGR-mediated)

The combined effect on TDEE appears meaningful

This practice is essential because the in-use time limit takes precedence over the printed expiration date

It does not ban anything by itself, but it signals where federal oversight of compounded GLP-1 is heading, which is why your enrollment timing and pharmacy questions matter more now than they did a year ago