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Bioavailability: NAC has an oral bioavailability of approximately 6-10% due to extensive first-pass metabolism, but the deacetylated cysteine that reaches tissues effectively drives glutathione synthesis [9]

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ALC has been studied in various conditions including neurological and cognitive disorders, and cardiovascular disease, as well as with respect to the fatigue and pain associated with conditions such as chronic fatigue syndrome and sciatica

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This is evidenced by the restoration to normal of fatty acid oxidation in muscle homogenates of certain L-Carnitine deficient patients