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Metformin primarily reduces hepatic glucose production and improves peripheral insulin sensitivity, while tirzepatide enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes satiety

If you take good care of it today, your future self will thank you

Reductions in liver fat are typical, with one study demonstrating an 86% decrease after 48 weeks

Their mechanisms are complementary, and combination protocols produce supra-additive GH secretion

If you discontinue the medication without establishing permanent dietary and lifestyle changes, hunger signals will gradually return to baseline, which can lead to regaining lost weight