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DFU are associated with multiple factors including DPN, PAD, foot deformities, history of foot ulcerations or amputations, nephropathy, etc., and are stratified at risk based on these risk factors

While war interrupted Zuelzer's work, it did not prevent others from continuing to investigate the use of pancreatic extracts for diabetes elsewhere

Figure 3: Structure of the pancreas with Islet of Langerhans, credit: BruceBlaus, Wikimedia Knowledge about the pancreas deepened further as a result of research by Ernest Starling and his brother-in-law William Bayllis, two British physiologists at UCL