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In each group, 30,000 cells were initially analysed using FACS and 21,00024,000 cells were eventually included in statistical analysis

, IL-6, MPO activity, and other mediators 1

For patients starting fresh, or switching from semaglutide for efficacy reasons, tirzepatide remains the more proven option at comparable weight loss levels without the dysesthesia risk

Weight LossEffective, But Not Universal - Up to ~47% of patients can achieve 15% weight loss - But response variesmany patients do not reach clinically meaningful thresholds - Compared to bariatric surgery, pharmacotherapy still has limitations Importantly, weight loss is largely fat-mass driven, with relative preservation of lean massif supported by proper nutrition and resistance training

Pushing your health concerns off because you don't want to go through the effort and disruption in your already stressful schedule