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The central mechanism also means semaglutide simultaneously improves glycemic control, reduces cardiovascular risk factors, and addresses the metabolic consequences of obesity not just the fat stores themselves
Some of those claims have genuine preclinical backing
For example, GLP-1 medications such as Tirzepatide and Semaglutide help many people eat fewer calories by reducing hunger
These senescent cells release harmful pro-inflammatory signals, known as the senescence-associated secretory phenotype (SASP), that damage surrounding tissues and disrupt overall organ function
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