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TB-500s defining and best-characterized action, by contrast, is exactly that: sequestration of monomeric G-actin through the LKKTETQ actin-binding motif, which regulates the cytoskeleton that drives cell migration
Results DMF activates the TSS pathway in SCD erythroblasts To investigate the mechanism of DMF on ferroptosis regulation, we conducted untargeted LC-MS using erythroblasts generated from CD34+ stem cells isolated from the peripheral blood of SCD patient
Renal cell death can be mediated by drug transporters that determine the selectivity for the tubular cell, mitochondrial damage, and drug metabolism (Barnett and Cummings 2018)
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