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Kishan KV et al
Lawrence, C
Your goal determines protocol intensity and duration
Jamshed 2011): Straining with at least 25% of bowel movements Lumpy or hard stools at least 25% of the time Sensation of incomplete emptying with at least 25% of bowel movements Sensation of an anal or rectal blockage with at least 25% of bowel movements The use of hands or fingers to facilitate at least 25% of bowel movements Fewer than three bowel movements per week Diagnostic tests are recommended if an underlying condition, such as hypothyroidism, may be a contributing factor
In the injection study, three 10-day cycles of 0.16 mg/kg over three months produced significant melanin-density increases by reflectance spectroscopy, with subjects who had the lowest baseline melanin showing the largest relative gains (Barnetson et al., 2006)
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