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Cardiovascular outcomes Semaglutide has a major advantage here, not because its cardiovascular effects are necessarily superior, but because they have actually been measured in a dedicated outcomes trial
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New England Journal of Medicine , 387 (3), 205216
Strict Rules for Oral Semaglutide Oral semaglutide must be taken under strict conditions: Empty stomach No food for 30 minutes Limited water intake Failure to follow this reduces absorption even further
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