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It is also the simplest amino acid, making it generally well-tolerated with minimal risk of adverse reactions
However, nearly all data come from lab and animal studies rather than controlled human trials, so claims about systemic hormone changes warrant caution
If metformin-induced diarrhea persists, your doctor may recommend extended-release metformin formulations, which produce fewer GI side effects than immediate-release versions
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However, I do find the dose a little low for the price as each bottle is only a months worth of supply and you can get an equivalent powder for a cheaper price
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