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In addition, you must meet one of the three clinical criteria set by CMS, measured at the time you start GLP-1 therapy: BMI of 35 or higher (and age 18 or older), or BMI of 30 or higher (and age 18 or older), plus one of the following: heart failure with preserved ejection fraction, uncontrolled high blood pressure (systolic above 140 or diastolic above 90 despite treatment with two blood pressure medications), or chronic kidney disease stage 3a or above, or BMI of 27 or higher (and age 18 or older), plus one of the following: prediabetes, a previous heart attack, a previous stroke, or symptomatic peripheral artery disease If you take a GLP-1 for another condition, the Bridge is not for you
Patients should strength-train 23 times weekly and consume at least 0.71g protein per pound of goal body weight to preserve lean mass
Fusco J et al (2017): GLP-1/Exendin-4 induces -cell proliferation via the epidermal growth factor receptor
Some trial participants reported increased nausea or fatigue during dose escalation
The drugs multifaceted impact on metabolism, body fat, and general well-being makes it a compelling choice for those who require more than lifestyle interventions
