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doi: 10.1096/fj.201801950r, 16
Neuronal and glial cell death in the necrotic region is linked to impaired blood flow and the disruption of the blood-brain barrier (BBB) integrity, potentially resulting in additional intracerebral haemorrhage and edema due to vascular leakage (Corps, Roth and McGavern, 2015)
It demonstrates higher potency at the GIP receptor, with comparatively lower potency at GLP-1 and glucagon receptors relative to their natural hormones
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