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While several clinical studies examined the favorable effect of reduced GSH short-term or long-term administration on alcohol-induced liver diseases (7276), the available literature on the effect of GSH on NAFLD is limited -see Table 1-, and the studies at hand are to be considered pilots (7779)

Interestingly, recent studies have proposed that DNA methylation can lead to the exclusion of a histone variant (H2A.Z), preferentially located at active gene promoter 36,37

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