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These treatments help reduce hunger, improve metabolic control, and lead to consistent, healthy weight loss when combined with proper nutrition and lifestyle support
The fact that the double-cysteine mutations only partially abolish the physiological function may imply that not all the expressed mutants have an intact disulfide bridge and that the observed conformation is only one possible inactive state on the cell surface, as supported by the EM data and MD simulations below
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doi: 10.1016/j.algal.2019.101617 29
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