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The nasal spray is being positioned for long-term weight management (obesity/overweight with comorbid conditions) , similar clinical population to current GLP-1 indications

Studies in mice found potent antinociceptive (pain-reducing) effects when the peptide was administered directly to the central nervous system

Vilks K, Videja M, Makrecka-Kuka M, Katkevics M, Sevostjanovs E, Grandane A, et al

For compounded vials of either drug, a 29G to 31G U-100 insulin syringe is more typical

The trade-off is that the entire vial is consumed in a single 10mg dose, meaning you cannot use it for dose escalation across multiple weeks