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Both DSIP and DSIP-CBBBP treatments increase serotonin levels significantly, suggesting their effectiveness in improving sleep effects, while CBBBP alone shows no significant impact on serum levels of melatonin, serotonin, dopamine, and glutamate
Additionally, cysteine starvation also activates the amino-acid starvation branch of the ISR, specifically through the GCN2-eIF2-ATF4 axis
Fatigue can emerge as caloric intake decreases
Occasionally, a bone marrow biopsy is done to help confirm the diagnosis
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