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Biomaterials (2013) 34:7895904

HUBERMAN: And indeed the growth hormone pulses from Hexarellin can be as great as two or three times more than with the other growth hormone secreting peptides that we've talked about

Specifically, GHK-Cu was found to be least possible to cause skin irritation, while CuCl 2 and Cu(OAc) 2 were found to induce the expression of various skin irritation biomarkers, i.e., IL-1, IL-8, FOSL1, and HSPA1A