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The EXAMINE and SAVOR-TIMI 53 studies were excluded from sensitivity analyses because DPP-IV inhibitor drugs did not show CV benefit in their individual trials
Retatrutide dosing protocol Retatrutide uses a similar escalation approach but with different dose levels
Skeletal muscle membrane preparation Wild-type RyR1 was purified from rabbit skeletal muscle (purchased from Pel-Freeze Biologicals), and R615C RyR1 was purified from muscle from pigs homozygous for this mutant (purchased from Boyle Farms, Moorehead, Iowa) as described before 38
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