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Reported side effects were mostly mild to moderate, mainly stomach symptoms similar to other GLP-1 medicines

Patients should increase home glucose monitoring frequency during the transition period and work with their healthcare provider to adjust or initiate alternative diabetes medications as needed

A 2022 review of 76 clinical trials noted participants who used GLP-1s specifically for weight loss, took a higher dose, and/or used the medication for more than 26 weeks were at a higher risk for gallbladder issues

This reduced binding may affect its bioavailability and interactions with target tissues in experimental models

Alert your provider immediately if you experience severe nausea, persistent vomiting, rapid weight changes, signs of hypoglycemia, or unexplained hyperglycemia while taking both medications