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2018, doi: 10.1007/s00296-018-4142-x Chourpiliadis, C., et al, "Use of Common Psychiatric Medications and Risk and Prognosis of Amyotrophic Lateral Sclerosis," JAMA Network Open, June 4, 2024, doi:10.1001/jamanetworkopen.2025.14437 Meron, M.K., et al, "GLP-1 receptor agonists and the risk of fragility fractures in older adults with type 2 diabetes," Journal of Clinical Endocrinology & Metabolism, Feb.10, 2026, doi: 10.1210/clinem/dgag056 Luo, Y., et al, "GLP-1 receptor agonists in eye disease: a comprehensive review of current research and future potential," BMC Ophthalmology, Jan

Nausea Nausea is the most frequently reported side effect of semaglutide therapy

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Unlike GLP-1 agonists, DPP-4 inhibitors do not affect satiety, gastric emptying, or induce weight loss