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Genistein protects against doxorubicin-induced cardiotoxicity through Nrf-2/HO-1 signaling in mice model
This makes the dual-agonist approach a preferred option for those who have struggled with side effects in the past
Clinical trials demonstrate an average weight loss of 1520% body weight by 72 weeks at therapeutic doses
We therefore postulated that IGF-1R mAbs could represent a viable therapeutic tool to target IGF-1 action, and potentially mimic the beneficial effects associated with diminished IGF-1 signaling observed in animal models
Potentiation of SDF-1 in experimental models may also exacerbate both retinopathy and neuropathy
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