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4 The effect of GLP-1RAs on the glycolysis in AD astrocytes

Furthermore, BPC 157 can also regulate the intestinal microbiota, improve intestinal barrier function, and alleviate symptoms such as irritable bowel syndrome (IBS)

### Tirzepatide: The Injectable Dual Agonist Tirzepatide (Zepbound/Mounjaro) remains the most effective GLP-1-based medication for weight loss, with 20-22.5% body weight reduction in the SURMOUNT-1 trial

Direct signals remain limited, and general stone prevention advice still applies

66,260 Thus, future clinical studies are necessary to assess the long-term safety of NAD + precursors in human therapeutics