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Briefly, metabolites from 3 10 6 cells were extracted on ice with 0.8 ml pre-cold 80% methanol (80 C), and cell rupture was achieved by a Bullet Blender Storm 24 (Next Advance, Troy, NY) with metal beads, followed by five freeze-thaw out cycles

Advantages Cost-effective and accessible Simple daily routine Often paired with other vitamins for enhanced impact Limitations Reduced absorption due to digestion Slower results compared to IV Comparing IV and Oral Skin Therapies Which Is More Effective for Skin Lightening