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Notably, Retatrutides 28% nausea rate compares favorably to semaglutides 44% nausea rate in comparable trials
So I think the bigger question for the ecosystem and society and for these companies is when those 1.5 million get the notice that they're not going to be able to be accessing their compounded drugs anymore, where are they going to go
This disruption can lead to impaired insulin secretion, abnormal glucose tolerance, and even diabetes
Nature (1983) 304:36871
The mechanism isn't fully understood but may relate to changes in cerebral blood flow from GH pulses
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