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Although AOM liraglutide (Saxenda) has been approved for treatment of obesity in adolescents since late 2020 ( 5 ), the approval of AOM semaglutide (Wegovy) in December 2022 for treatment of obesity for adolescents prompted new excitement ( 6 )

Most people get the recommended dietary allowance of B12 (2.4 micrograms for adults, more for pregnant or lactating women and the elderly) through their daily intake of food

Symptoms potentially related to blood pressure changes require clinical assessment

Since then, the landscape of G-agonists has evolved considerably with respect to both new drugs (triple agonists) and clinical impact beyond obesity per se