While choline was first isolated in the 1860s, its biological importance wasnt fully appreciated until the 20th century.26 In 1998, the Institute of Medicine officially classified it as an essential nutrient highlighting its vital roles in liver health, cell signaling, and brain development.11 Since then, research on choline has expanded significantly, influencing dietary guidelines and supplement formulations.1 Different types of choline supplements Choline appears in supplements under several different names
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The researchers noted it is crucial in the removal and detoxification of carcinogens thanks to its antioxidant effects (12)
Plasma advanced glycation end products are associated with incident cardiovascular events in individuals with type 2 diabetes: a case-cohort study with a median follow-up of 10 years (EPIC-NL)