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If you miss 2 or more consecutive doses, contact your healthcare provider (you may need to re-titrate)

Heart Rate Increase: Both adults and pediatric patients experienced mean increases in resting heart rate of 1 to 4 beats per minute (bpm) in semaglutide patients compared to placebo in clinical trials

Table of Contents How Retatrutide Is Administered and Why Route Matters Retatrutide is administered as a once-weekly subcutaneous injection, not orally, because it is a peptide molecule that digestive enzymes would break down before it could be absorbed into the bloodstream

These can also make you feel a lot of pain

PLoS ONE 6 , e17361 (2011)