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No saturation behavior for GSSG was previously detected for the fusion construct between rxYFP and ScGrx1 31 , which makes sense considering that PfGrx and many other glutaredoxins are at least two orders of magnitude more active than ScGrx1 (Table 1) 14,56
Conclusion 12
Best Use Case Glutathione is best suited for addressing hyperpigmentation, dullness, and uneven tone, whereas NAC is better for long-term antioxidant balance and detoxification support
Several observations from this system strongly support a contact-dependent mechanism
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