As tirzepatide was compared to controls, the hazard ratios for MACE-4 were 0.80 (95% confidence interval [CI], 0.571.11), cardiovascular death was 0.90 (95% CI, 0.501.61), and all-cause death was 0.80 (95% CI, 0.511.25) [2]
Both Wegovy and Ozempic, which mimic the hormone GLP-1, are given as weekly injections, as are rival drugs from Eli Lilly, called Zepbound and Mounjaro
10.1096/fj.09-147421 49 MamgainR.KosticM.SinghF
Each year of delay loses a cohort of patients who would have entered the programme that year
Cost-Effectiveness: Outsourcing with a third party manufacturer such as H&I Critical Care saves the company from huge amounts of investments put into infrastructure, machinery, and labor, thereby reducing overall cost of operation