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This peptide is a newer player in the realm of peptide therapies

Table 10: Results at Week 26 in a Trial Comparing TRESIBA U- 200 to Insulin Glargine U-100 in Adult Patients with Type 2 Diabetes Mellitus on OAD(s)* Study F TRESIBA Administered at the Same Time Each Day in Insulin Nave Adult Patients as an Add on to One or More of the Following Oral Agents Metformin, Sulfonylurea, Glinides or Alpha Glucosidase Inhibitors The efficacy of TRESIBA was evaluated in a 26 week randomized, open label, multicenter trial in Asia in 435 insulin nave patients with type 2 diabetes mellitus inadequately controlled on one or more oral antidiabetic agents (OADs) at baseline

The medications come in pre-filled pens with ultra-fine needles, minimising discomfort

This is benign and typically resolves between injections or as the protocol continues

Further research is warranted to investigate the potential roles of weight loss, TSH fluctuations, and levothyroxine dose adjustment after GLP-1RA in mediating the cardiovascular risk