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doi: 10.1002/dmrr.3070 30 AliSStoneMAPetersJLDaviesMJKhuntiK

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However, silybin, EGCG, myricetin, baicalein, curcumin, and quercetin significantly changed AUC 0- and the metabolite-maternal ratio (MR) of 4- hydroxy-tamoxifen, indicating that it can significantly increase the bioavailability of TAM and affect the formation of 4-hydroxy-tamoxifen (Shin et al., 2006