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No effects on maternal and fetal survival or morphology were observed in both studies at doses of up to 200 mcg/kg/day (6.5 times a 0.6 mg dose received by a 60 kg patient based on body surface area) nor were there effects in the pre- and postnatal development study on parturition, postnatal survival, growth, development or behavior, up to the highest dose tested of 10 mcg/kg/day (0.3 times a 0.6 mg dose received by a 60 kg patient, based on body surface area)

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Melanin is what gives skin its color and helps protect us from UV rays

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However, this possibility seems unlikely, because over comparable periods of time, treatment with GLP-1 receptor agonists (which also enhance signaling through the GLP-1 pathway) reduced the risk of atherosclerotic ischemic events [51, 52]

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