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Anecdotally, some patients have seen greater weight-loss totals
Critically, perioperative metabolic reprogramming is driven by acute DAMPs/mtDAMPs exposure, ischemia-reperfusion-induced hypoxia/reoxygenation, and the inflammatory cytokine milieunot by oncogenic transformation
Oral semaglutide already exists in the UK as Rybelsus, although its licensed use is for type 2 diabetes rather than obesity
An important consideration : Women with PCOS who have not been having regular periods may experience a return to fertility when starting GLP-1 treatment and losing weight
But this can be minimized with a smart, proactive strategy
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