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Most protocols last 46 weeks, but duration depends on the injury, health goals, and medical advice

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They also cost time and money, and in some cases expert groups have decided that routine screening does not clearly improve health for everyone

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This leads to dose-dependent weight loss (typically 8-15% in monotherapy trials), with additive effects when combined with GLP-1 agonists like semaglutide due to complementary mechanisms on energy balance and gastrointestinal function