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Review Article Abstract Introduction Retatrutide for Treatment of Obesity Retatrutide for Treatment of Type 2 Diabetes Effects of Retatrutide on Cardiovascular Risk Factors Safety of Retatrutide Effect of Retatrutide on Heart Rate Advantages of Retatrutide Limitations of Retatrutide Conclusions and Current Needs References Retatrutide as a Novel Treatment for Obesity and Type 2 Diabetes Nasser Mikhail 1* and Soma Wali 2 1* and Soma Wali 2 1 Endocrinology Division, Olive View-UCLA Medical Center, David-Geffen UCLA Medical School, USA 2 Department of Medicine, Olive View-UCLA Medical Center, David-Geffen UCLA Medical School, USA Submission: July 18, 2023