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Methionine alone cannot compensate for choline deficiency, and choline cannot bypass impaired SAMe synthesis if methionine is depleted

Hassan R (2016) Possibilities and limitations of intravital imaging

7 According to a study done by Bernardo Yusta from the University of Toronto in Toronto, Canada and colleagues, treatment of diabetic rats with exendin-4 can significantly reduce biochemical markers of islet endoplasmic reticulum (ER) in beta cells