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Cycling protocols (8 weeks on, 4 weeks off) prevent this adaptation and maintain sensitivity

Nicholson-Weller A, Klickstein LB (1999) C1q-binding proteins and C1q receptors

For these patients, being able to stop thinking about food is a relief, and can lead to an overall healthier lifestyle

Gastrointestinal events occurred most frequently during the dose escalation period and typically improved with continued treatment

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