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What this adds up to clinically: GLP-1s are best understood as treating the underlying metabolic disease, not just as a weight loss intervention
Reduced Food Intake Because semaglutide curbs appetite, some people unintentionally under-fuel their bodies
It's important to consult with a healthcare professional before starting treatments to assess your suitability and discuss potential risks
For LC-MS analysis, samples were thawed on ice-water bath, then 40 L of whole blood was injected into 450 L cold extraction solvent comprising of mixture of Acetonitrile:Methanol:Milli-Q water in ratio 40:40:20 according to protocol described in Presterud et al 35
As a corollary, there may be additional effects on the BBB in GBM due to the effect of epileptogenesis on pericytes, please see Lscher and Friedman (2020) and Yamanaka et al
