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In the IMPACT trial, pemvidutide achieved mean weight losses of 4.8% and 5.8% with 1.2 and 1.8 mg doses respectively at 24 weeks, compared to 0.5% with placebo, with weight loss curves showing no evidence of plateauing, suggesting continued benefit with longer treatment [49-51]
The agency announced plans to restrict GLP-1 ingredients intended to be used in these compounded medications
But reassuring is not the same as proven safe
Sitagliptin exerts an antinflammatory action
General rule: 28-30 days for most reconstituted peptides When peptides are reconstituted with bacteriostatic water and properly refrigerated, the standard shelf life is approximately one month
