If a day is missed, the research-sensible response is simply to resume the next scheduled dose, not to double up, because there is no acute deficit to make good and doubling only departs from the documented figure
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Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements