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doi:10.1155/2009/532640
( Its still important to maintain healthy nutrition, so dont decrease your calories by too much
Merck's MK-0893, Lilly's LY2409021, and Pfizer's PF-06291874 all reached Phase 2 and all failed - transaminase elevations, LDL increases, weight gain
Improved circulation and reduced inflammation also suggest benefits for the gut-brain axi, possibly easing brain fog, mood swings, and cognitive fatigue that plague so many patients
Some considerations for lower-BMI use include: helping to break long-standing weight loss plateaus, weight maintenance after dieting, and reduction in compulsive or binge eating
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