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Patients with a BMI of 30, or a BMI of 27 with one weight-related medical condition (like high blood pressure or type 2 diabetes), are candidates for weight loss medications like GLP-1s

SGLT2 inhibitors or basal insulin may be added based on cardiovascular and renal risk, with tirzepatide (Mounjaro) also NICE-approved for type 2 diabetes

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PT-141, also known as bremelanotide, is a synthetic peptide that acts as an agonist for melanocortin receptors in the brain's arousal pathways

This additional amount delivered to cells can also have a positive impact on skin brightening