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The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)

And the signal that turns on GNRH is Kispeptin

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Its studied for its ability to promote tissue healing, regeneration of injured tissue, accelerated repair and wound healing, nerve damage healing, and regulate inflammation

During high-estrogen phases, mast cells may release more histamine into the bloodstream