If MB therapy is contemplated in a woman of reproductive age, a pregnancy test is often performed, and effective contraception should be recommended during treatment
As the primary factors for the reduced anticancer effect 1) the reduced delivery and uptake of the anticancer agent, 2) the need for the conversion of molecular oxygen (O 2 ) into reactive oxygen species (ROS), 3) the preferred therapeutic effect against highly proliferating cells, which is reduced under hypoxic conditions, or 4) adaptation of the cancer cells by promoting cell survival and upregulating certain resistance pathways, has been suggested 1,2,3,4,5
(2019) 10:2051 doi:10.3389/fimmu.2019.02051
Highly Effective: Unlike oral supplements, which lose immense potency as they pass through your digestive tract, our B12 injections deliver the vitamin directly into your bloodstream
Endpoints: wound closure rate (planimetry, ImageJ), granulation tissue (histological scoring), collagen organization (Picrosirius red), re-epithelialization (H&E), tensile strength (mechanical testing)