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The null findings on memory reported by Feter et al may be related to exercise intensityas increases in muscle mass are not necessarily intensity dependent (Mcleod et al., 2024), but evidence does support that intensity mediates exercise-related neurogenesis and neuroplasticity in interval and aerobic exercise models (Marko et al., 2022

GI side effects in clinical trials typically resolved within 23 weeks, but if symptoms persist beyond four weeks at a reduced dose, discontinuation is warranted

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Glucagon on its own can raise blood sugar, but when its balanced with GLP-1 and GIP activity, it appears to create broader metabolic effects

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