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In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

Core antioxidant role GSH participates in the detoxification of peroxides and other reactive species through enzyme systems such as glutathione peroxidase, thereby helping protect cellular lipids, proteins, and DNA from oxidative damage

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