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After removal, bile flows continuously from the liver directly into the small intestine, rather than being stored and released in response to meals

Some higher-dose trials reported weight loss averages up to 20%

Approved in 2017 to treat tardive dyskinesia, Ingrezza is a selective vesicular monoamine transporter 2 inhibitor

Healthcare providers should reassess the benefit-risk profile periodically and consider discontinuation if patients do not achieve clinically meaningful weight loss or experience intolerable adverse effects

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