restarting glp 1 Should You Stop and Restart a GLP-1? What to Know Understanding GLP-1 Pauses and Restarting

PMID 28373912 Pickart L, et al

But some researchers titrate too slowly, sitting at sub-therapeutic doses for months

Thomsen MS, Johnsen KB, Kucharz K, Lauritzen M, Moos T

Potential risks Serious risks and adverse events include: Allergic reaction to the medications or dye used in the injection Shoulder infection Depigmentation of the skin around the injection site (a whitening of the skin) Local fat atrophy around the injection site (thinning of the skin) Rupture of a tendon located in the path of the injection Nerve damage near the shoulder joint Bleeding at the injection site In addition to the above, corticosteroid injections increase the risk of: High blood pressure High blood sugar Decreased immune function Decrease in bone mineral density Bone infection (osteonecrosis) Reproductive hormone imbalance Metabolic changes (eg, increased appetite, weight gain, and fluid retention) These risks are typically associated with higher doses of corticosteroids, multiple injections, and for people with underlying medical conditions such as diabetes and heart problems

De Jonge CJ, et al