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The implications of centrally produced, neuromodulatory GLP-1 in the context of GLP-1RAs are uncertain, as the degree to which signals from pre-proglucagon neurons/endogenous GLP-1 system and GLP-1RA activity converge on shared downstream targets is unclear 6 and may in fact occur independently 7
GLP-1 is a hormone that is released into the bloodstream in response to food consumption
To view a copy of this license, visit About this article Cite this article Klement, R., Fink, M
These fasted mutants also exhibited physiological changes similar to those observed in wild-type fasted animals, including reduced body size and enhanced motility (Supplementary Fig
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