Transdermal-delivery research has repeatedly demonstrated that microneedle-created channels can increase the skin permeation of hydrophilic and larger molecules by many-fold compared with application to intact skin the exact magnitude depends on needle length, density, molecule size, and how soon after treatment the active is applied
Remarkably, 54% of those initially classified with obesity moved into the non-obese BMI range by study end vs
For research purposes, they are commonly reconstituted using bacteriostatic (BAC) water (sterile water with 0.9% benzyl alcohol) to prevent bacterial growth
Of course, if you have any questions outside of those check-ins, you can log into your Hone account to message your doctor any time
The deciding factor is always the same: if the vial will be used once, sterile water is clean, simple, and sufficient its only when multi-dose use comes into play that bacteriostatic water becomes the necessary standard